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Stieglitz Lab @

The mission of our lab is to improve outcomes for children with Ras-driven leukemia. We focus our studies on juvenile myelonomocytic leukemia (JMML) which is exclusively initiated by mutations in the Ras pathway.

Lab Members and Projects

Kira Feldman

Projects:
iPSCs
CyTOF

Julia Meyer

Projects:
Guthrie Card Screening
Bioinformatics

Elliot Stieglitz

Study Chair of ADVL1521:
Phase 2 Trial of Trametininb in JMML

Anna Hecht De Gutierrez

Projects:
iPSCs
CBL Registry
Pretransplant chemo for JMML

Alex Chao

Projects:
Novel Fusions in JMML
PDX models of JMML

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Publications and Funding

Number of Mutations Predicts Outcome

Pre-HCT Chemo in JMML

FLT3 Fusion in JMML

DNA Methylation Predicts Spontaneous Resolution

Subclonal Mutations in SETBP1 Predict Outcome

We are hiring research technicians and post-docs. Email us!