Stieglitz Lab @

The mission of our lab is to improve outcomes for children with Ras-driven leukemia. We focus our studies on juvenile myelomonocytic leukemia (JMML) which is exclusively initiated by mutations in the Ras pathway.

ABOUT

SERVICES

Lab Members and Projects

Sherin Xirenayi

Projects: ZNF384 Fusions Mouse Models Tissue Banking

Julia Meyer

Projects: All things Bioinformatics

Elliot Stieglitz

Study Chair of ADVL1521 Study Chair of TACL2020-004

Jose Rivera

Projects: Mouse models of JMML and AML Flow cytometry

Juwita Huebner

Projects: CAR-T cells in JMML JAK/STAT inhibition

CLIENTS

Selected Publications

Genomic Landscape of JMML

Nature Genetics 2015

DNA Methylation Predicts Outcome in JMML

Nature Communications 2017

Definitions of DNA Methylation in JMML

Clinical Cancer Research 2021

Trametinib in Relapsed and Refractory JMML

Cancer Discovery 2024

Funding Sources

CONTACT

We are hiring research technicians and post-docs. Email us!